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Lampl Y, Paniri Y, Eshel Y, Sarova-Pincha I (1990) Alkaline phosphatase level in CSF in various brain tumors and pulmonary carcinomatous meningitis

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It uses the low dose of X-rays to detect masses, microcalcifications, and architectural distortions suggestive of malignancy

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Currently recognized contributors to this phenomenon include increased oxidative stress, elevated expression of MMPs, degradation of collagen and elastin, heightened inflammatory responses, and melanin deposition, among others