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We demonstrate here that our single agents are highly effective at low concentrations on their own and show substantial synergistic effects when combined

Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin that plays a crucial role in various bodily functions

This suppression may lead to reduced luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion, affecting ovulation timing and menstrual predictability

Insulin therapy involves subcutaneous injections (under the skin) and is typically used to manage Type 1 diabetes

The mutants did not indicate any evidence of growth deficiency in vitro