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doi:10.1016/j.juro.2008.10.015

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7.4 Therapeutic potential of microglial regeneration Furthermore, microglial regeneration as a therapeutic approach holds significant promise, with adult brain-resident nestin-positive progenitor cells capable of rapidly proliferating and differentiating into ramified microglia under CSF1R signaling

The aberrant activity of these enzymes is closely linked with the pathogenesis of a wide range of diseases, not only cancers but also metabolic, inflammatory, and neurological disorders, underscoring the therapeutic relevance of targeting these pathways