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FIGURE 2 With the ability to import cysteine from and export glutamate into the extracellular environment, SLC7A11 can exert effects on the interplay with cancer cells and TME, which in turn influence tumor growth and response to cancer therapies

To compare this refolding buffer with conventional refolding conditions, refolding was also performed in a refolding buffer containing 3/1 mM GSH/GSSG