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doi: 10.3389/fimmu.2022.816282 40 WalkerEJWalkerSM

The GPX4 inhibitors could downregulate GPX4 and selectively reduce the residual CRC persister cell pool in vitro

S.KleinC

10.1007/s11033-018-4465-4 142

The first step is to shift the phosphate to C-2 of glycerate, converting 3-phosphoglycerate into 2-phosphoglycerate, catalyzed by the enzyme phosphoglycerate mutase (see Fig