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(etc) [DOI] [PubMed] [Google Scholar] 65.Komohara Y., Fujiwara Y

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Its anti-inflammatory effects on NFkB a key mediator of age-related inflammatory disease and its DNA repair activity suggest potential relevance in broader regenerative medicine, though most of these applications remain under investigation

doi: 10.1124/pr.112.006361

Intestinal injury and gut permeability in sickle cell disease

When iron levels are excessively high, the RANKL/OPG ratio increases, leading to the promotion of osteoclast maturation and bone resorption through TFR1-mediated iron uptake ( Figure 2 )