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These stimuli activate cell surface receptors, including Toll-like receptors (TLRs) and TNF receptors (TNFRs), which recruit adaptor proteins such as MyD88 and TRIF to form signalling complexes [41]

This inhibition, in turn, led to the remodeling of the colon mucosal barrier and its associated metabolites demonstrating its therapeutic potential in maintaining the integrity of the colon mucosa [80]

Boosting with a second protein injection did not enhance this response

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This procedure is performed under local anaesthetic and sedation as a day surgery procedure, and typically takes 5-10 minutes