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As shown in Figure S8, we first treated HCECs seeded on coverslip A with FITC-labeled CeNPs for 24 h, and then this coverslip was co-cultured with a second coverslip (coverslip B) in fresh culture medium for another 24 h

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(B) Interaction of selective estrogen receptor degraders (SERDs) with ER

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To this end, we infused healthy C57BL/6J mice with 1-[ 13 C 1 ]-serine for 4 hours via the jugular vein to label intracellular intermediates in the transsulfuration and glutathione synthesis pathways (Figure 2A)