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has received research grants, travel grants, consulting honoraria or lecturers honoraria from AbbVie, Bayer Schering Pharma, Biogen IDEC, Celgene, Dr

Disrupting this interaction by substituting E134 and D137 in BubR1 with positively charged residues individually or combinatorially had no effect on kinetochore localization, but almost completely abolished SAC signaling, a phenotype similarly observed when replacing Cdc20 R286 with a negatively charged residue (Supplementary Fig

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