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Methods Cell lines and cell culture Murine WEHI, 32D (32Dcl3), WT, and T315I-BcrAbl-transformed 32D cells were generously provided by Dr

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3.1 Metabolic reprogramming in T-cell malignancy Malignant T-cells show various alterations in terms of their metabolic reprogramming to fuel their survival and vigorous proliferation and to meet these demands rewire their several signaling pathways like Glycolysis and glutaminolysis pathways to meet the demands of energy, 3.1.1 Glucose metabolism in malignant T-cells Aerobic glycolysis or Warburg effect is the phenomenon of glucose fermentation into lactate or lactic acid in the presence of oxygen i.e., in aerobic conditions

KBs are able to provide an additional energy source and may therefore improve energetics in the failing heart

DOI: 10.18632/oncotarget.25355 49

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