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Efforts to optimize drug delivery systems, such as nanoparticle-based carriers, may enhance the precision and efficacy of ferroptosis inhibitors while minimizing off-target effects

doi: 10.1016/j.ccell.2023.02.016 2 PetrovaTVKohGY

For the isASO-ID SILAC-MS/MS experiments in panel a-f, detected proteins were colored according to their biological function as P-body component (gold), paraspeckle protein (red) and the annotated GO terms DNA binding (orange) and RNA binding (blue)

Glutathione levels decreased under iron exposure in both WT and gsh strains, consistent with an oxidative stress response

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