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In the H 2 O 2 -induced melanocyte model, Hyp protected melanocytes from oxidative damage by regulating the PI3K/Akt pathway, inhibiting p38 phosphorylation and suppressing mitochondrial apoptotic signaling, which included upregulation of the Bcl-2/Bax ratio and expression of Akt, and downregulation of caspase 3, p38 (Yang et al., 2016)

A thorough clinical evaluation is essential before a diagnosis is confirmed or any treatment programme begins

The major physiological and psychological effects associated with methamphetamine use

Islam MdR, Rauf A, Akash S, Trisha SI, Nasim AH, Akter M, Dhar PS, Ogaly HA, Hemeg HA, Wilairatana P, Thiruvengadam M (2024) Targeted therapies of curcumin focus on its therapeutic benefits in cancers and human health: Molecular signaling pathway-based approaches and future perspectives

Patches that are primarily restricted to the face and distal extremities are indicative of acrofacial vitiligo

Lysophosphatidylcholine induces oxidative stress in human endothelial cells via NOX5 activation - implications in atherosclerosis