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There is some evidence that early-onset depression shows stable cognitive deficits, whereas late-onset depression involves broader cognitive impairment and faster decline that may be associated with underlying neurodegenerative pathology, as shown by some but not all studies [30, 35,36,37]

Mild redness may appear for 1 to 2 hours post-treatment and resolves on its own

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After repeated washing the bound fraction was eluted with 250 mM imidazole (Fischer) in lysis buffer containing 10% glycerol (Acros)

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