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The Bead Ruptor Homogenizer model was also shown to induce altered sleep/awakening cycle-related behavior, concordant to what has been reported in the clinical population ( An additional Drosophila model was designed by Allada lab, using Drosophila closed head injury (dCHI) ( Drosophila to be injured is immobilized and placed in a modified 200 ml pipette in front of the block