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Sulforaphane possesses anti-inflammatory characteristics by decreasing TNF- and IL-6 levels, inhibiting COX-2 expression, TLR4 oligomerization, TLR4/MyD88 pathway and blocking the degradation of IL-1R-associated kinase-1, NF-B, and IFN regulatory factor 3 activation (227, 228)

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& Ettinger, M

Our study only focuses on the long-term treatment and we will not discuss in this paper the management of the crisis, which is based on antimigraine agents, antiemetics and glucose infusion to avoid the additional effect of ketosis on vomiting

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