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In the validation cohort, endogenous controls and the differential expression of one of the identified miRNAs were confirmed

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The butyrate kinase pathway utilizes phosphotransbutyrylase and butyrate kinase to convert butyryl-CoA to butyric acid, and this pathway is derived from Coprococcus [34]

Davies, CBE, MB, ChB, MD, Professor of Diabetes Medicine at the University of Leicester Diabetes Research Centre, United Kingdom, adding that nearly one-third achieved weight loss 20% with CagriSema, compared to 0.2% with placebo

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doi:10.3389/fphar.2025.1551843