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Primary metabolism of aflatoxin B 1 Once inside the body and for toxicity to occur, AFB 1 undergoes enzymatic conversion to electrophilic endo and exo stereoisomers of AFB 1 -8,9-epoxide by the action of mixed function mono-oxygenase enzyme systems, CYPs are an intensively studied family of enzymes with currently approximately 4,000 known members

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It could be seen that glutathione might promote the metabolism of pesticides in tomatoes by regulating the interaction between the UGT gene and transcription factors

Cisplatin is a nonspecific cytotoxic drug targeting the cell cycle by inhibiting the DNA replication process in cancer cells and damaging the structure of the cell membrane, endowing it with broad spectrum of anticancer efficacy

Most hepatocytes appeared to have deeply stained nuclei and congested sinusoids