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This process regulates intestinal calcium and phosphorus absorption, promotes bone mineralization, maintains calcium and phosphorus homeostasis, and participates in physiological processes such as immune regulation, cell proliferation, and differentiation, thereby safeguarding human health ( 2 D 3 inhibits the activity of CYP2R1 in the liver and 1-hydroxylase in the kidney via a negative feedback mechanism, thus preventing excessive vitamin D synthesis and activation, and maintaining vitamin D metabolic homeostasis ( Figure 2 )

Depressive disorders, with heterogeneous symptoms, are highly prevalent among MS patients (2)

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Successful use of cefiderocol to treat a multidrug-resistant Stenotrophomonas maltophilia ventilator-associated pneumonia in an extremely preterm neonate