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Similar to the effects of NNMT overexpression, hepatocytes treated with MNAM exhibited significant increases in glucose production and expression of Sirt1, G6pc, and Pck1

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Fyfe J.C., Madsen M., Hjrup P., Christensen E.I., Tanner S.M., de la Chapelle A., He Q., Moestrup S.K

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Additionally, inhibition of the mammalian target of rapamycin (mTOR) with everolimus reduced the levels of tau and amyloid precursor protein/amyloid (APP/A) and improved cognitive function