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The anti-apoptotic activity of TB-500 may involve the reduction of early cell death initiation signals and activation of the survival kinase Akt through complex formation with PINCH and integrin-linked kinase

15 , C33 (2007)

Phenotypes resembling human ALS have been successfully replicated in SOD1 mutant mice and through the targeted deletion of the hypoxia response element (HRE) from the promoter of the mouse VEGF gene (Thakur et al

Hodi FS, Lawrence D, Lezcano C, Wu X, Zhou J, Sasada T, et al

Rats fed a high-fat diet supplemented with black cardamom had increased levels of important antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferase (GST) in both their liver and heart [22]

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