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NA-Cis-AuNRs induce oxidative stress and promote apoptosis To further elucidate the cytotoxic mechanisms of NA-Cis-AuNRs on other cellular responses, a series of in vitro assays was performed to evaluate morphological changes, ROS generation, and cell death in MDA-MB-231 cells, as shown in Fig

However, ROS levels remain at nonlethal levels in normal cells, thus enabling specific targeting of cancer cells

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Approved as sedative, analgesic & muscle relaxant for veterinary use in dogs, cats, horses, deer, elk

IGF-1R Knockout Confirms Essential Role (Liu et al., 2006) Conditional knockout of IGF-1R in mouse follicles produced retarded hair growth, disorganized hair shaft structure, and aberrant hair cycle timing

Consequently, viruses exploit mitochondrial networks to subvert antiviral immunity, reprogram cellular metabolism, and ensure successful propagation