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If all the radioactivity is excreted with feces the patient is not able to absorb the vitamin, but if it enters the body the capacity for uptake of B12 remains

As you can see, each approach has its strengths and limitations

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Edited by Professor Boris Zhivotovsky Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

doi:10.1128/JB.00687-12

Enzymatic reaction of chlorotrifluoroethene with glutathione: 19F NMR evidence for stereochemical control of the reaction