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doi: 10.1016/S0960-9822(03)00189-1 65 JurewiczJMajewskaJBergAOwczarekKZajdelRKaletaDet al

But B12 supplements don't seem to have any effect on people already at normal levels

138 At the same time, some studies have found that after activating GPR109A by niacin, it can reduce the secretion of proinflammatory cytokines made by macrophages, monocytes and epithelial cells