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Standing inside his suburban Houston home nearly a year later, Castaeda tallies the cost of the destructive floods to himself and his uninsured neighbors: one couple in their 70s let their home go into foreclosure

Professor Ngs research contributions to AOD-9604 development include: Synthesis and characterization of the modified C-terminal growth hormone fragment with enhanced stability Design of the tyrosine N-terminal modification to improve peptide stability and half-life Preclinical studies demonstrating lipolytic effects in obese animal models Advancement of the peptide through multiple phases of clinical development Investigation of mechanisms underlying beta-3-adrenergic receptor modulation His work established the foundation for understanding peptide-based approaches to metabolic regulation, though clinical translation ultimately proved unsuccessful

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Meddings JB, Jarand J, Urbanski SJ et al (1999) Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat