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6.7 Chronic hepatopathy Patients with chronic liver diseases have shown that disturbances of antioxidant parameters in their blood may be the cause of peroxidative damage to hepatocytes

( 3.3 Intestinal permeability The intestinal barrier and intestinal permeability are essential factors in health and disease ( The GM and pathogens frequently enhance barrier permeability by modifying the construction and function of tight junctions (TJ)which seal the paracellular spacevia the production of proteases that break TJ proteins or modify the cytoskeleton ( Firmicutes -to- Bacteroidetes ratio and restored alpha diversity alongside increased concentrations of SCFAsincluding acetate, propionate, and butyrate

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