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The dual nature of type I and type II interferons

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For example, resveratrol-loaded solid lipid nanoparticles (SLNs) were characterized as having a homogeneous size distribution and mean diameter of approximately 155 nm and no significant size differences due to resveratrol incorporation

The increase in ROS can also affect the apoptosis and metabolism of glioma cells via the JNK-regulated metabolic pathway and ataxia telangiectasia mutated (ATM)-Yes-associated protein 1 (YAP1)-driven apoptotic pathway ( Celastrol is one of the most important active ingredients of the traditional Chinese medicine Tripterygium wilfordii , which activates the JNK pathway and ROS production and inhibits the activities of mechanistic targets of rapamycin (mTOR) and Akt kinases, significantly increasing apoptosis and autophagy in glioma cells (Liu et al., 2019)

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