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What we DO know, however, is that only 20% (or even less) of the people with symptomatic B12 deficiency have anaemia or altered size of the red blood cells

It can injure the mitochondria, which is the energy producing cells

So in other words, people who never had trouble before would suddenly have anxiety attacks, panic attacks, shaky shakes, tremors, pseudo seizuresand even real seizuresterrible insomnia, and different kinds of brain fog

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This mechanistic insight is strongly supported by in vivo evidence showing that anti-OPN antibodies, which mimic the effect of blocking thrombin-cleaved OPN, replicate a tumor suppression phenotype in knock-in mice engineered with a thrombin cleavage-resistant form of the protein [271]