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Initially described as a pro-atherogenic molecule due to its proliferative role in VSMC, it was further demonstrated that the effect of IGF-I on VSMC was to compensate for local apoptosis, and that, overall, IGF-I is not pro-atherogenic in native arteries but anti-atherogenic [320], mainly through enhanced nitric oxide production [308]

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Disseminated intravascular coagulation: a devastating systemic disorder of special concern with COVID-19

The study observed that serum LPS levels in STEMI patients peaked on the second day after symptom onset

Nicotine, a major component of tobacco, has been shown to inhibit lymphocyte proliferation and differentiation, leading to suppressed antibody formation [20]

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