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Journal of Pediatrics, 130(4), 468-475

A study by Nikolic et al

doi: 10.1017/jns.2016.41 45 ParvinK.HasanuzzamanM.BhuyanM

Currently, several methods that effectively inhibit the occurrence of parthanatos by clearing lipid peroxides have been confirmed, such as using -tocopherol (-TOC) and ALOX12/15 inhibitors [144]

These trials are designed to establish long-term efficacy and safety across the metabolic-disease spectrum

Third, tumor heterogeneity means that not all cells within a tumor depend equally on glycolysis, allowing resistant subpopulations to survive and repopulate the tumor