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Kole L, Sarkar M, Deb A, Giri B

As an emerging concept, reductive stress complicates, but expands our understanding of the cellular redox environment

In vivo and in vitro findings revealed that H 2 S directly deactivates the inhibitor of kappa B kinase subunit beta (IKK) by sulfhydrating its Cys179, thereby preventing NF-B activation and reducing endothelial cell inflammation in PH (Zhang D