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SKU: 42908926231 · From reganhouse.co.nz

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5.3 Metabolic and barrier dysfunction The oral microbiota dysbiosis associated with periodontitis disrupts the intestinal microenvironment through metabolic regulation and impaired barrier function, contributing to the pathogenesis of depression

For instance, spontaneously hypertensive rats (SHRs) displayed pathophysiological changes in the gut, including decreased numbers of goblet cells and villi length and increased fibrosis, compared to age-matched normotensive Wistar Kyoto (WKY) controls (172)

(2003a)

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