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In insulin-responsive tissues, the equilibrium between MI and its epimer D-chiro-inositol (DCI) is important because insulin promotes the epimerase-mediated conversion of MI into DCI, which is then incorporated into GPI-anchored proteins and released as DCI-IPGs following insulin stimulation (137)

Efficacy and safety of liraglutide and semaglutide on weight loss in people with obesity or overweight: A systematic review

Although tinnitus is possibly the effect of physical damage to the auditory cortex and sensory hair cells, it creates major psychological distress in patients, leading to sleep deprivation, depression, and anxiety

The supposed benefits of this diet would range from supporting digestive processes, to maintaining microbiota balance, contrasting overweight, and preventing inflammation and autoimmunity [140, 141]

Altogether, these proinflammatory changes in vascular homeostasis are known to promote proatherogenic accumulation of both inflammatory leukocytes and LDL in the vascular wall 36 (Fig