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Longitudinal data from the Parkinsons Progression Markers Initiative (PPMI) cohort further demonstrate that AQP4 genetic variation influences glymphatic efficiency, with the rs162009 variant emerging as a prognostic marker for cognitive decline in PD ( Further genetic evidence also underscores astrocytic vulnerability in PD

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Eating heavy, spicy, or fatty meals late at night can increase the likelihood of acid reflux and indigestion by the time morning arrives

No statistical methods were used to predetermine sample sizes but our sample sizes are similar to those reported in our previous publications 8,57

Activating cgas-sting axis contributes to neuroinflammation in cvst mouse model and induces inflammasome activation and microglia pyroptosis