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Anti-CD38 antibodies mediate anti-myeloma activity through multiple mechanisms of action both in patients with RRMM and with newly diagnosed MM, although immunomodulatory effects may be greater in earlier disease settings in which the immune system has not been affected by prior treatments [85]

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Figure 1 is an example of where a hospital provides all the contractual data on how the price is calculated, but in a way that a reasonable, objective MRF user would not be able to interpret it and use it to draw comparisons

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The majority of patients are females ranging from 16 to 25 years of age

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