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Currently, the main combination therapy focuses on vaccine combined with other drugs to enhance the anti-tumor effect

Volume 10, Apr

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Nrf2 plays a pivotal role in redox homeostasis and is involved in key metabolic processes, including xenobiotic detoxification, iron and heme metabolism, lipid and carbohydrate metabolism, proteostasis, and the regulation of cell death pathways ( The activity of Nrf2 is primarily regulated by Kelch-like ECH-associated protein 1 (Keap1), a cytosolic repressor that acts as a substrate adaptor for a Cullin-3-based E3 ubiquitin ligase complex