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In contrast to S100A7, S100A15 is not able to either bind to Jab1 or interact with RAGE to activate respective signaling pathways

[DOI] [PubMed] [Google Scholar] 75.Mahawar K.K., Reid A., Graham Y., Callejas-Diaz L., Parmar C., Carr W.R., Jennings N., Singhal R., Small P.K

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275 Inflammatory molecular signalling pathways in both the central nervous system and the periphery can affect brain connections and synaptic function by affecting components including microglia, complement factors, cytokines and their receptors, MET receptors, and major histocompatibility complex class I molecules (MHCI) (Fig