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While the spheroids treated with Ru(II)-OH or NP2 in a 1% O 2 atmosphere majorly consisted of living cells, the spheroids treated with NP4 in a 1% O 2 atmosphere consisted of dead cells (Fig

In this study, we successfully achieve tumor-targeted aggregation of an aggregation-induced emission photosensitizer (AIE-PS), TB m A, with the catalysis of a tumor-overexpressed enzyme, -Glutamyl Transferase (GGT)

Additionally, Ca 2+ involvement and the highly active mitochondrial oxidative phosphorylation processes in astrocytes and oligodendrocytes facilitate the substantial release of ROS

Additionally, C75 induces apoptosis across various cancer cell lines, suggesting its potential as a therapeutic target for cancer (71)

reported that in a rat model of hepatic I/R injury, the depletion of Nrf2 aggravated inflammation and lead to oxidative stress and apoptosis 30

When the body becomes overwhelmed by too many CICs, the complexes accumulate in the liver, leading to impaired liver function