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Among amino acids that make up proteins, nine cannot be synthesized from other compounds and must be obtained from food

Tian et al., 2022) have confirmed that Bifidobacteria can be used to treat depressive symptoms, but the underlying mechanisms have not been completely elucidated, which may be related to reducing the abundance of pathogenic bacteria, exerting the anti-inflammatory effects, improving the permeability of intestinal barrier, regulating the tryptophan levels, affecting 5-hydroxytryptamine (5-HT) synthesis, and regulating hypothalamus-pituitaryadrenal (HPA) axis (Figure 1)

Kiefer and Copley, 2002)

Fox Foundation (Therapeutic Pipeline Program #9998 (Cullen)), the Department of Veterans Affairs (BLR&D Merit Review I01-BX003748 (Cullen)), the National Institutes of Health (BRAIN Initiative U01-NS094340 (Cullen) & T32-NS043126 (Harris)), and the National Science Foundation Graduate Research Fellowship (DGE-1321851 (Struzyna))

Br J Haematol 148(2):195204 Allen LH (2009) How common is vitamin B-12 deficiency

Moreover, 1000 g/mL GE completely reverses A-induced cytotoxicity ( There is also evidence indicating that Gastrodin can improve memory in mice, reduce the deposition of A amyloid plaques, the number of astrocytes and activated microglial cells, and decrease the expression of TNF- and IL-1 in N9 cells