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The study found that the intestinal microbial imbalance in T2D was characterised by a decrease in the abundance of Bifidobacteria, Bacteroides, Faecalis, Akkermansia and Byrysia ross, while an increase in Rumen coccus, Fusobacterium and Blautella (52)

In a depleted body, the ROS accumulate, which can cause immediate mitochondrial damage and trigger the severe, delayed symptom flares characteristic of PEM

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