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Deficiencies in mitochondrial GR activity have been implicated in various neurodegenerative conditions, aging processes, and metabolic disorders

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Given the impact of xCT on antigen-presenting potential of DCs, and the role of xCT in cancer exhaustively described by previous reports (including ferroptosis (72, 73), nutrient dependency (74), and cancer therapy (75)) (70), a new potential regulatory axis is proposed

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