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Awareness of this issue by medical professionals, specifically pharmacists, is particularly important because of the common frequency of exposure of the diabetic population to both metformin and either PPIs or H 2 RAs, especially since the two latter medications are readily available as over-the-counter versions

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Reusable bottles, especially plastic ones, are the perfect breeding ground for bacteria, mold, and even chemical leaching if ignored for too long

Age effects and folate status, a modifier of vitamin B 12 metabolism, are also considered (Fedosov et al., 12 status, cB 12 , is defined as: cB 12 = log10((holo-TC.B 12 )/(MMA.tHcy))(age factor) (Fedosov et al., 12 status provides five distinct ranges of diagnostic value, which are summarized in Table 1

Research shows 6 percent of people 60 years old and over are classed as deficient in vitamin B12, and this only increases with age

Lurz, E