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7.2 Personalized antioxidant strategies: One size does not fit all As the understanding of oxidative stress deepens, it is clear that uniform supplementation strategies may be insufficient

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however, the combination might produce delayed healing and less-than-ideal outcomes

SYRCLEs risk of bias tool for animal studies

For prevention of contrast-induced acute kidney injury, a meta-analysis found misleading beneficial associations that were lost when analysis was restricted to larger studies (52) , and mechanistic studies showed that oral NAC is poorly absorbed with no renoprotective effects (53)