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Under conditions of moderate alcohol consumption where blood alcohol levels average 0.060.08 percent and decrease 0.010.02 percent per hour, an alcohol clearance rate of 45 hours would coincide with disruptions in sleep maintenance in the second half of an 8-hour sleep episode

Kem DC, Weinberger MH, Higgins JR, Kramer NJ, Gomez-Sanchez C, Holland OB

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In these 3 studies, PROZAC 60 mg, but not 20 mg, was statistically significantly superior to placebo in reducing the number of binge-eating and vomiting episodes per week