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Additionally, the -1-hydroxilase enzyme, which converts inactive metabolite of VD (25(OH) D3) to the active form (1,25(OH)2D3), is expressed by the majority of immune cells such as macrophages [112]

Luo X, Gong HB, Li ZC, Li DD, Li ZX, Sun J et al (2024) Phospholipid peroxidation in macrophage confers tumor resistance by suppressing phagocytic capability towards ferroptotic cells

ACS Nano 18 , 1388513898 (2024)

Procaccini C, De Rosa V, Galgani M, Abanni L, Cal G, Porcellini A, et al

SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis

The medication reaches high concentrations in skin tissue, making it particularly effective against the localized infection that develops at the bite site before spreading throughout the body