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AM is deeply grateful to the Department of Medicinal Chemistry in the Faculty of Pharmacy, Ain Shams University, for providing the software used in the virtual screening and molecular docking work

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In vitro studies can provide information regarding drugenzyme and drugtransporter interactions

*Correspondence: Reza Faridi-Majidi, [email protected] Braeckmans, [email protected] This article was submitted to Molecular Diagnostics and Therapeutics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

7 CNA cancer gene tumours drive distinct transcriptional programs

However, clinical data are limited, and more rigorous trials are needed to confirm these findings and clarify mechanisms