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NAFLD progresses when multiple factors cause liver damage, including oxidative stress, mitochondrial dysfunction, inflammatory cytokines, and intestinal dysbiosis (Gou et al., 2023)

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While researching why young blood had a rejuvenating effect on older liver tissue, Pickart identified this small copper-binding peptide as the responsible factor

During aging and in many chronic illnesses, our cells lose the capacity to make enough gamma-glutamylcysteine (GGC), which means cells do not produce sufficient glutathione (GSH) to protect against oxidative stress [1]

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