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Analyses of the systematic reviews and meta-analyses of the RCTs investigating the clinical outcomes of RES treatments in T2DM patients

Older adults may require more consistent supplementation to bridge this gap and support healthy ageing

In a mouse model of HF, quercetin promotes the de succinylation of isocitrate dehydrogenase (IDH2) through SIRT5, maintains mitochondrial homeostasis, and improves myocardial fibrosis, thereby reducing the incidence of HF (134)

The damage or dysfunction of this cellular organelle is linked to electron leakage increasing O 2 generation

Ferroptosis has been proposed as one mechanism of neuron injury in response to irradiation and has been observed in hippocampal neurons of irradiated mice [48]