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The effect of Berberine on weight loss in order to prevent obesity: A systematic review

CONVERGE consortium

In transgenic models, it reduced fibril formation by 62% and striatal deposits by 41%, while also improving motor function without eliciting significant immunogenicity

Other factors such as Cl - , Ca 2+ , and Na + ion channels/transporters also interact with the luminal pH and collectively regulate the lysosomal acidic environment