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High-grade gliomas like glioblastoma multiforme (GBM) exhibit especially robust neutrophil infiltration, and these TANs have been implicated in tumor progression and recurrence (72, 75, 76)

Global Prevalence [Ref] Approximately 25% of the global population carries the MTHFR C677T mutation

While less than 1% of patients experience cardiac toxicity, 50% of patients who experience a cardiac event discontinue immunotherapy due to the high mortality rate

(1) Treatment of growth hormone deficiency and dwarfism Growth hormon deficiency and dwarfism are diseases caused by insufficient secretion of growth hormon, and patients may experience symptoms such as growth retardation and short stature

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Another approach for future studies is the use of food intake biomarkers instead of FFQ