During the review, the committee will likely consider: The extensive body of published research on GHK-Cu (decades of studies) Safety data for both injectable and topical routes The clinical rationale for copper peptide therapy in anti-aging and wound healing Quality control considerations for compounding GHK-Cu formulations Public comments from patients, dermatologists, anti-aging practitioners, and pharmacies Given GHK-Cu's long history of use and substantial research base, many in the peptide therapy community are cautiously optimistic about a positive PCAC recommendation particularly for the topical route
That dual role is part of why the research base touches so many systems: skin, hair follicles, wound beds, lung, gut, and bone in animal and cell models
Int J Mol Med 39:208216 Yan J, Luo A, Gao J et al (2019) The role of SIRT1 in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery
Hydrafacial A Hydrafacial before a GHK-Cu protocol session optimizes the skin surface for better serum penetration and addresses congestion and dullness that can mask peptide results
If using both, apply them at different times for example, vitamin C in the morning and GHK-Cu at night or use separate treatment days
Effects of intracerebroventricular injection of delta sleep-inducing peptide (DSIP) and an analogue on sleep and brain temperature in rats at night